Trial document




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  DRKS00015692

Trial Description

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Title

Relevance of polyunsaturated fatty acids for outcome after out of hospital cardiac arrest

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Trial Acronym

ROSC

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URL of the Trial

[---]*

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Brief Summary in Lay Language

[---]*

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Brief Summary in Scientific Language

After successful cardiopulmonary resuscitation, the fatty acid concentrations of patients with preclinical cardiovascular arrest will be analyzed by mass spectrometry. In addition, the enzymes and metabolic pathways important for fatty acid metabolism will be determined using gene array investigations. One year after cardiovascular arrest, a telephone interview is planned in which the current neurological status of the patient will be determined. Retrospectively, an evaluation of the findings collected and documented during the inpatient stay as part of the clinical routine will be carried out.
It is planned to correlate the obtained molecular biological data with the survival and the neurological outcome.

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Organizational Data

  •   DRKS00015692
  •   2018/12/12
  •   [---]*
  •   yes
  •   Approved
  •   137/18, Ethik-Kommission der Medizinischen Fakultät der Rheinischen Friedrich-Wilhelms-Universität Bonn
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Secondary IDs

  •   U1111-1223-3000 
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Health Condition or Problem studied

  •   I46.0 -  Cardiac arrest with successful resuscitation
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Interventions/Observational Groups

  •   Correlation of Docosahexaenic acid concentration with 1 year survival after cardiac arrest
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Characteristics

  •   Non-interventional
  •   Observational study
  •   Single arm study
  •   Open (masking not used)
  •   [---]*
  •   Uncontrolled/Single arm
  •   Basic research/physiological study
  •   Single (group)
  •   N/A
  •   N/A
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Primary Outcome

Survival

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Secondary Outcome

Neurologic outcome modified ranking scale

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Countries of Recruitment

  •   Germany
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Locations of Recruitment

  • University Medical Center 
  • other 
  • other 
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Recruitment

  •   Actual
  •   2019/08/10
  •   150
  •   Multicenter trial
  •   National
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Inclusion Criteria

  •   Both, male and female
  •   18   Years
  •   110   Years
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Additional Inclusion Criteria

Cardiac Arrest

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Exclusion Criteria

none

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Addresses

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    • Universitätsklinikum Bonn
    • Sigmund-Freud-Str. 25
    • 53127  Bonn
    • Germany
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    • Klinik und Poliklinik für Anästhesie und Operative Intensivmedizin Universitätsklinikum Bonn
    • Mr.  PD Dr. med.  Markus  Velten 
    • Sigmund-Freud-Str. 25
    • 53127  Bonn
    • Germany
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    end of 1:1-Block address contact scientific-contact
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    • Klinik und Poliklinik für Anästhesie und Operative Intensivmedizin Universitätsklinikum Bonn
    • Mr.  PD Dr. med.  Markus  Velten 
    • Sigmund-Freud-Str. 25
    • 53127  Bonn
    • Germany
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Sources of Monetary or Material Support

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    • Klinik und Poliklinik für Anästhesie und Operative Intensivmedizin Universitätsklinikum Bonn
    • Mr.  PD Dr. med.  Markus  Velten 
    • Sigmund-Freud-Str. 25
    • 53127  Bonn
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Status

  •   Recruiting ongoing
  •   [---]*
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Trial Publications, Results and other Documents

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* This entry means the parameter is not applicable or has not been set.