Trial document
This trial has been registered retrospectively.
DRKS00013947
Trial Description
Title
Using virtual reality to reduce cognitive biases in psychosis
Trial Acronym
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URL of the Trial
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Brief Summary in Lay Language
Cognitive distortions are associated with the formation and maintenance of delusions. Studies show that correcting cognitive distortions (e.g. jumping to conclusions bias) may also reduce psychotic symptoms. The aim of this study is to investigate whether the correction of overconfidence in false memories via a virtual reality intervention leads to an improvement of delusional ideation in people with a psychosis.
Brief Summary in Scientific Language
Cognitive distortions are associated with the formation and maintenance of delusions. Studies show that correcting cognitive distortions (e.g. jumping to conclusions bias) may also reduce psychotic symptoms. The aim of this study is to investigate whether the correction of overconfidence in false memories via a virtual reality intervention leads to an improvement of delusional ideation in people with a psychosis. A randomised, controlled design was used. The participants complete four different virtual scenarios. Afterwards they are asked for previously shown persons and objects. The intervention group receives feedback on errors in the recognition task to correct possible overconfidence in false memories. The control group receives no feedback. The goal is to decrease overconfidence in false memories by providing corrective experiences and consequently reduce delusional ideation.
Do you plan to share individual participant data with other researchers?
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Description IPD sharing plan:
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Organizational Data
- DRKS00013947
- 2018/06/25
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- yes
- Approved
- SM 112015, Deutsche Gesellschaft für Psychologie
Secondary IDs
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Health Condition or Problem studied
- F20 - Schizophrenia
- Psychosis
Interventions/Observational Groups
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Feedback group (participants receive immediate feedback for errors in a recognition task).
The participants undergo four different virtual scenarios. Afterwards, they are asked for previously shown persons and objects. The intervention group receives feedback on errors in the recognition task to correct possible overconfidence in false memories. -
No feedback group (participants do not receive feedback for errors).
The participants undergo four different virtual scenarios. Afterwards, they are asked for previously shown persons and objects. The control group receives no feedback on their performance (e.g. errors) in the recognition task.
Characteristics
- Interventional
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- Randomized controlled trial
- Blinded
- assessor
- Control group receives no treatment
- Treatment
- Parallel
- II-III
- N/A
Primary Outcome
Reduction of psychotic symptoms, measured with:
Four weeks after baseline:
Positive and Negative Syndrome Scale (PANSS),
Psychotic Symptom Rating Scales (PSYRATS)
Immediatly after the VR (virtual reality) Intervention:
Paranoia Checklist,
Community Assessment of Psychic Experiences
Secondary Outcome
Feasibility and accaptence of the virtual reality and head-mounted display, measured immediatly after the VR intervention:
Simulation Sickness Questionnaire
Countries of Recruitment
- Germany
Locations of Recruitment
- Medical Center
Recruitment
- Actual
- 2016/02/08
- 90
- Monocenter trial
- National
Inclusion Criteria
- Both, male and female
- 18 Years
- 55 Years
Additional Inclusion Criteria
- current or past psychotic episode (verified via the MINI)
- informed consent
Exclusion Criteria
- history of seizures or epilepsy
- other neurologic disorders
Addresses
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start of 1:1-Block address primary-sponsor
- Asklepios Klinik Nord - Wandsbek
- Prof. Dr. Matthias Nagel
- Jüthornstr. 71
- 22043 Hamburg
- Germany
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end of 1:1-Block address contact primary-sponsor -
start of 1:1-Block address scientific-contact
- Asklepios Klinik Nord - Wandsbek
- Mona Dietrichkeit
- Jüthornstraße 71
- 22043 Hamburg
- Germany
end of 1:1-Block address scientific-contactstart of 1:1-Block address contact scientific-contact- + 49 -40 - 18 18 87 1999
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- m.dietrichkeit at asklepios.com
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end of 1:1-Block address contact scientific-contact -
start of 1:1-Block address public-contact
- Asklepios Klinik Nord - Wandsbek
- Mona Dietrichkeit
- Jüthornstraße 71
- 22043 Hamburg
- Germany
end of 1:1-Block address public-contactstart of 1:1-Block address contact public-contact- + 49 -40 - 18 18 87 1999
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- m.dietrichkeit at asklepios.com
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end of 1:1-Block address contact public-contact
Sources of Monetary or Material Support
-
start of 1:1-Block address materialSupport
- Asklepios proresearch
- Lohmühlenstraße 5
- 20099 Hamburg
- Germany
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Status
- Recruiting ongoing
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Trial Publications, Results and other Documents
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