Trial document





This trial has been registered retrospectively.
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  DRKS00012518

Trial Description

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Title

Biomarkers of inflammation / Medical RNomics

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Trial Acronym

Bioinflame / Medical RNomics

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URL of the Trial

[---]*

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Brief Summary in Lay Language

The aim of this study is to examine new laboratory values to make the diagnosis of inflammatory and infectious diseases easier and faster, so that the following treatment can be initiated earlier and more precisely. For this purpose, blood samples taken routinely are analysed.

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Brief Summary in Scientific Language

It is intended to check descriptively whether biomarkers allow a more precise and faster classification of infectious diseases. Therefore, expecially the specific inflammation proteins IL-6, IL-33 and TSLP, the leukocyte-surface-markers CD136, MR, SRA, CCR7 and the expression of miRNas (miR) in leukocytes are going to be analysed.

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Organizational Data

  •   DRKS00012518
  •   2017/07/13
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  •   yes
  •   Approved
  •   EA2/030/09, Ethik-Kommission der Charité -Universitätsmedizin Berlin-
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Secondary IDs

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Health Condition or Problem studied

  •   C34 -  Malignant neoplasm of bronchus and lung
  •   J18 -  Pneumonia, organism unspecified
  •   N39 -  Other disorders of urinary system
  •   B54 -  Unspecified malaria
  •   J45 -  Asthma
  •   J44 -  Other chronic obstructive pulmonary disease
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Interventions/Observational Groups

  •   patients suffering from an acute infectious disease: assesment of several putative biomarkers of inflammation at the time of inclusion
  •   healthy subjects: assesment of several putative biomarkers of inflammation at the time of inclusion
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Characteristics

  •   Non-interventional
  •   Observational study
  •   Other
  •   Open (masking not used)
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  •   Other
  •   Basic research/physiological study
  •   Other
  •   N/A
  •   N/A
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Primary Outcome

descriptive assesment of putative inflammatory markers by laboratory meassurements

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Secondary Outcome

/

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Countries of Recruitment

  •   Germany
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Locations of Recruitment

  • University Medical Center 
  • University Medical Center 
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Recruitment

  •   Actual
  •   2009/06/29
  •   130
  •   Multicenter trial
  •   National
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Inclusion Criteria

  •   Both, male and female
  •   18   Years
  •   no maximum age
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Additional Inclusion Criteria

suspicion of infectious disease

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Exclusion Criteria

dialysis patient, sepsis

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Addresses

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    • Philipps-Universität MarburgInstitut für Lungenforschung
    • Hans-Meerwein-Str. 2
    • 35043  Marburg
    • Germany
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    • Philipps-Universität MarburgInstitut für Lungenforschung
    • Mr.  Prof. Dr. med.  Bernd  Schmeck 
    • Hans-Meerwein-Str. 2
    • 35043  Marburg
    • Germany
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    • UKGM, Standort Marburg, Klinik für Innere Medizin mit Schwerpunkt Pneumologie
    • Ms.  Ursula  Boas 
    • Baldingerstraße
    • 35043  Marburg
    • Germany
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Sources of Monetary or Material Support

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    • Philipps-Universität Marburg, Institut für Lungenforschung
    • 35043  Marburg
    • Germany
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Status

  •   Recruiting ongoing
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Trial Publications, Results and other Documents

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* This entry means the parameter is not applicable or has not been set.