Trial document





This trial has been registered retrospectively.
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  DRKS00011892

Trial Description

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Title

Collection of neurophysiological parameters during tension- vs. electrical current based electromyography

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Trial Acronym

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URL of the Trial

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Brief Summary in Lay Language

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Brief Summary in Scientific Language

The aim of the current study is to evaluate if neuromuscular and functional correlates of movement control can be assessed with potential-based electromyography (EMG) in patients suffering from neurological disorders. Therefore, central nervous control and motor output is measured in multiple sclerosis patients. With electromyography, peripheral nervstimulation and kinetic assessement methods, muscle responses of lower limb muscles, spinal excitability as well as mobility, fine motor acurracy and individiual perception of motor control are quantified. Secondary it is tested, if the modulation of neuromusucular control can be evaluated with potential-based EMG as well. To realize that, the application of whole body vibration is a valuable method, because it has been shown to have an impact on spinal and supraspinal movement control.

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Organizational Data

  •   DRKS00011892
  •   2017/04/25
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  •   yes
  •   Approved
  •   189/15, Ethik-Kommission der Albert-Ludwigs-Universität Freiburg
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Secondary IDs

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Health Condition or Problem studied

  •   G35 -  Multiple sclerosis
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Interventions/Observational Groups

  •   Two-legged stance on a vibrating platform (side-alternating vertical sinusoidal, frequency ca. 30 Hz, amplitude ca. 2 mm)
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Characteristics

  •   Interventional
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  •   Single arm study
  •   Open (masking not used)
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  •   Uncontrolled/Single arm
  •   Other
  •   Single (group)
  •   N/A
  •   N/A
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Primary Outcome

Assessment of neuromuscular activation patterns (muscular disbalances) with potential-based electromyography. outcome measure: muscle output, spinal excitability. assessment method: potential-based EMG and peripheral nervstimulation during different paradigms regarding movement control.

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Secondary Outcome

Assessment of the modulation of neuromuscular activation patterns (muscular disbalances) with potential-based electromyography. outcome: muscle output, spinal excitability. assessment method: potential-based EMG and peripheral nervstimulation during different paradigms regarding movement control
modulation method: whole body vibration.

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Countries of Recruitment

  •   Germany
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Locations of Recruitment

  • other 
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Recruitment

  •   Actual
  •   2015/12/15
  •   15
  •   Monocenter trial
  •   National
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Inclusion Criteria

  •   Both, male and female
  •   35   Years
  •   70   Years
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Additional Inclusion Criteria

orthopaedic healthy, diagnosed MS with EDSS between 3.5-6.5

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Exclusion Criteria

chronic/ orthopaedic diseases, acute injuries of the locomotor apparatus, pregnancy, metal in the head (except mouth), pacemaker, neuronal disorders (epilepsy, depression, stroke)

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Addresses

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    • Albert-Ludwigs-Universität FreiburgInstitut für Sport und Sportwissenschaft
    • Mr.  Prof.Dr.  Albert  Gollhofer 
    • Schwarzwaldstraße 175
    • 79117  Freiburg
    • Germany
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    • Albert-Ludwigs-Universität FreiburgInstitut für Sport und Sportwissenschaft
    • Ms.  Anne  Krause 
    • Schwarzwaldstraße 175
    • 79117  Freiburg
    • Germany
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    • Albert-Ludwigs-Universität FreiburgInstitut für Sport und Sportwissenschaft
    • Ms.  Anne  Krause 
    • Schwarzwaldstraße 175
    • 79117  Freiburg
    • Germany
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Sources of Monetary or Material Support

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    • Aenne Speck Stiftung
    • 66119  Freiburg/ Saarbrücken
    • Germany
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Status

  •   Recruiting complete, follow-up complete
  •   2016/12/31
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Trial Publications, Results and other Documents

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* This entry means the parameter is not applicable or has not been set.