Trial document





This trial has been registered retrospectively.
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  DRKS00009828

Trial Description

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Title

Overcoming Disembodiment: The Effect of Movement Therapy on Negative Symptoms in Schizophrenia - A Multicenter Randomized Controlled Trial

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Trial Acronym

TESIS HD1

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URL of the Trial

https://tesisnetwork.wordpress.com/

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Brief Summary in Lay Language

Negative symptoms such as flat affect and low attention and interaction motivation of patients with schizophrenia can not be treated well with medication or conventional group therapy. Since the alienation from the body plays and important role in schizophrenia, embodied therapies, such as Dance and Movement Therapy (DMT) or Body Psychotherapy (BPT), may be helpful to address and explain the mental illness. The present randomized controlled study examines the effectiveness of manualized movement therapy (BPT/DMT) on the negative symptoms, particularly on flat affect, of patients with schizophrenia. Sixty-eight (N=68) out-patients with a diagnosis of a schizophrenia spectrum disorder were randomly assigned to either the treatment group (n = 44, 10 weeks of BPT/DMT) or the control group (n = 24, without BPT/DMT). Changes in negative symptoms were analyzed controlling for side effects of antipsychotic medication.
After ten weeks of movement therapy, patients had significantly lower negative symptoms (SANS total score, blunted affect, attention). Effect sizes were moderate and mean symptom reduction in the treatment group was 20.65%. Compared to recent findings concerning the efficacy of anti-psychotic medication the results indicate that embodied therapies, such as BPT/DMT, are currently the only treatment consistently reducing negative symptoms of schizophrenia.

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Brief Summary in Scientific Language

Objective. Negative symptoms of patients with Schizophrenia are highly resistant to medical treatment or conventional group therapy. Apprehending schizophrenia as a form of disembodiment of the self, a number of scientists have argued that the approach of embodiment and associated embodied therapies, such as Dance and Movement Therapy (DMT) or Body Psychotherapy (BPT), may be more suitable to explain the psychopathology underlying the mental illness and to address its symptoms. Hence the present randomized controlled trial aimed to examine the effectiveness of manualized movement therapy (BPT/DMT) on the negative symptoms of patients with schizophrenia.
Method. A total of 68 out-patients with a diagnosis of a schizophrenia spectrum disorder were randomly allocated to either the treatment (n = 44, 10 weeks of BPT/DMT) or the control condition (n = 24, treatment as usual (TAU)). Changes in negative symptom scores on the Scale for the Assessment of Negative Symptoms (SANS) were analyzed using Analysis of Covariance (ANCOVA) with Simpson-Angus Scale (SAS) scores as covariates in order to control for side effects of antipsychotic medication.
Results. After ten weeks of treatment (BPT/DMT or TAU), patients receiving movement therapy had significantly lower negative symptom scores (SANS total score, blunted affect, attention). Effect sizes were moderate and mean symptom reduction in the treatment group was 20.65%.
Conclusion. Compared to recent findings concerning the efficacy of anti-psychotic medication the results indicate that embodied therapies, such as BPT/DMT, are currently the only treatment consistently reducing negative symptoms in patients with schizophrenia.

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Organizational Data

  •   DRKS00009828
  •   2015/12/30
  •   [---]*
  •   yes
  •   Approved
  •   S-156/2012, Ethik-Kommission I der Medizinischen Fakultät Heidelberg
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Secondary IDs

  • [---]*
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Health Condition or Problem studied

  •   F20-F29 -  Schizophrenia, schizotypal and delusional disorders
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Interventions/Observational Groups

  •   Intervention Group (Manualized Body Psychotherapy / Dance Movement Therapy á 20 sessions x 1.5 hours in 10 weeks delivered by three dance movement therapists in eight groups at three psychiatric setting in Southern Germany; Manual of F. Röhrich & N. Papadoupolous, 2000)
  •   Waiting List Control Group (TAU; in this case no treatment other than their usual medication, all patients were out-patients).
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Characteristics

  •   Interventional
  •   [---]*
  •   Randomized controlled trial
  •   Blinded
  •   assessor, data analyst
  •   Control group receives no treatment
  •   Treatment
  •   Parallel
  •   N/A
  •   N/A
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Primary Outcome

Improvement of Negative Symptoms, particularly Blunted Affect, measured with the Scale for the Assessment of Negative Symptoms (SANS), before and after 20 sessions (10 weeks) of movement therapy

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Secondary Outcome

Improvement of Well-Being, measured with the Heidelberg State Inventory (HSI; Koch, Morlinghaus, & Fuchs, 2007), before and after 20 sessions (10 weeks) of movement therapy

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Countries of Recruitment

  •   Germany
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Locations of Recruitment

  • University Medical Center 
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Recruitment

  •   Actual
  •   2012/05/30
  •   100
  •   Multicenter trial
  •   National
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Inclusion Criteria

  •   Both, male and female
  •   14   Years
  •   65   Years
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Additional Inclusion Criteria

Diagnosis of a schizophrenia spectrum disorder IDC-10: F20.x, F25.x;
Outpatient;
Stable medication

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Exclusion Criteria

phase of acute psychosis;
history of brain trauma, neurological or internistic disease, affecting movement abilities;
withdrawal of consent;
alcohol or substance abuse or dependency within 24 months prior to participation or substance induced psychosis;
IQ < 70;
pronounced language barriers;

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Addresses

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    • Psychiatrische Universitätsklinik Heidelberg EU-Projekt TESIS
    • Mr.  Prof. Dr. Dr.   Thomas   Fuchs 
    • Vossstr. 4-6
    • 69123  Heidelberg
    • Germany
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    • Alanus Hochschule Alfter
    • Ms.  cand. MSc.  Lily  Martin 
    • Villestr. 3
    • 53347  Alfter
    • Germany
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    • SRH Hochschule HeidelbergAlanus Hochschule Alfter
    • Ms.  Prof. Dr.  Sabine  Koch 
    • Maria-Probst-Str. 3
    • 69123  Heidelberg
    • Germany
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    • Universitätsklinikum Heidelberg
    • Mr.  Prof. Dr. Dr.  Thomas  Fuchs 
    • Vossstr. 4-6
    • 69115  Heidelberg
    • Germany
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Sources of Monetary or Material Support

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    • Europäische Union TESIS-Projekt (PI: Prof. Dr. Dr. Thomas Fuchs, Heidelberg) Directorate-General for Research and Innovation European Commission
    •  
    • Covent Garden, Place Rogier, 16
    • B-1049  Brüssel
    • Belgium
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    •   [---]*
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    • Universitätsklinikum Heidelberg
    • Im Neuenheimer Feld 672
    • 69120  Heidelberg
    • Germany
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Status

  •   Recruiting complete, follow-up complete
  •   2015/03/31
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Trial Publications, Results and other Documents

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