Trial document





This trial has been registered retrospectively.
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  DRKS00006958

Trial Description

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Title

Jugular vein expansion by positive end-expiratory pressure and positioning in emergency department patients

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Trial Acronym

JUVEX PEPPER

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URL of the Trial

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Brief Summary in Lay Language

Impact of non-invasive ventilation and positioning of patient on cross-setional area of the right jugular vein.

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Brief Summary in Scientific Language

Our investigation measures the impact of non-invasisive ventilation applying positive end-expiratory pressure on the cross-sectional area of the right jugular vein in three different positions (Trendelenburg, 0° and 30° upright).

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Do you plan to share individual participant data with other researchers?

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Description IPD sharing plan:

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Organizational Data

  •   DRKS00006958
  •   2014/11/19
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  •   yes
  •   Approved
  •   4099-06/14, Ethikkommission der Friedrich-Schiller-Universität Jena an der Medizinischen Fakultät
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Secondary IDs

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Health Condition or Problem studied

  •   Z04.8 -  Examination and observation for other specified reasons
  •   patients presented to the emergency department of our hospital by pre-hospital emergency systems.
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Interventions/Observational Groups

  •   Impact of non-invasive ventilation and positioning of patient on cross-sectional area of the right jugular vein [positionings: 0° (flat) supine position, trendelenburg (approx. -15°), and 30° head-of-bed elevation]
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Characteristics

  •   Interventional
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  •   Single arm study
  •   Open (masking not used)
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  •   Other
  •   Basic research/physiological study
  •   Single (group)
  •   N/A
  •   N/A
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Primary Outcome

cross-sectional area of right jugular vein measured by ultra-sound

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Secondary Outcome

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Countries of Recruitment

  •   Germany
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Locations of Recruitment

  • University Medical Center 
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Recruitment

  •   Actual
  •   2014/08/29
  •   91
  •   Monocenter trial
  •   National
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Inclusion Criteria

  •   Both, male and female
  •   18   Years
  •   no maximum age
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Additional Inclusion Criteria

Presentation in ED by prehospital emergency teams and acute or acute-on-chronic state of disease.

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Exclusion Criteria

minors, pregnant women, need for immediate treatement in intensive care unit or operation theater (or similar), intubated patients, patients with contra-indications for positionings or non-invasive ventilation, patients under supervision of authorities (inmates of penitentiaries or similar), patients with impaired communication abilities including insufficient knowledge of the German language, missing allowance of ED medical staff.

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Addresses

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    • Klinik für Anästhesiologie und IntensivtherapieUniversitätsklinikum Jena
    • Erlanger Allee 101
    • 07747  Jena
    • Germany
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    • Zentrale NotaufnahmeUniversitätsklinikum Jena
    • Mr.  Dr. med.  Christian  Hohenstein 
    • Erlanger Allee 101
    • 07747  Jena
    • Germany
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    • Klinik für Anästhesiologie und IntensivtherapieUniversitätsklinikum Jena
    • Mr.  Dr. med.  Hendrik  Rüddel 
    • Erlanger Allee 101
    • 07747  Jena
    • Germany
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    • Klinik für Anästhesiologie und IntensivtherapieUniversitätsklinikum Jena
    • Mr.  Dr. med.  Hendrik  Rüddel 
    • Erlanger Allee 101
    • 07747  Jena
    • Germany
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Sources of Monetary or Material Support

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    • Klinik für Anästhesiologie und IntensivtherapieUniversitätsklinikum Jena
    • Erlanger Allee 101
    • 07747  Jena
    • Germany
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Status

  •   Recruiting complete, follow-up complete
  •   2016/12/21
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Trial Publications, Results and other Documents

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