Trial document





This trial has been registered retrospectively.
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  DRKS00006259

Trial Description

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Title

Radio biologic profiling for a biologic stratified radiochemotherapy of head and neck tumors: a multicenter retrospective study of the Deutsches Konsortium für Translationale Krebsforschung

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Trial Acronym

HNprädbio-retro

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URL of the Trial

[---]*

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Brief Summary in Lay Language

This retrospective study is initiated to find a radio-biological profiling for a biologically stratified chemoradiation in head and neck squamous cell carcinoma.

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Brief Summary in Scientific Language

The retrospective study is initiated to find a radio-biological profiling for a biologically stratified chemoradiation in head and neck squamous cell carcinoma. For this purpose, samples are collected from the respective centers. The collection of all tissue samples is performed in Dresden. There, multi-tissue arrays are produced.

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Organizational Data

  •   DRKS00006259
  •   2016/02/18
  •   [---]*
  •   yes
  •   Approved
  •   213/13, Ethik-Kommission der Albert-Ludwigs-Universität Freiburg
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Secondary IDs

  • [---]*
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Health Condition or Problem studied

  •   Squamous-cell carcinoma
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Interventions/Observational Groups

  •   The retrospective study is initiated to find a radio-biological profiling for a biologically stratified chemoradiation in head and neck squamous cell carcinoma. For this purpose, samples are collected from the respective centers. The collection of all tissue samples is performed in Dresden. There, multi-tissue arrays are produced.
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Characteristics

  •   Non-interventional
  •   Other
  •   Other
  •   Open (masking not used)
  •   [---]*
  •   Other
  •   Prognosis
  •   Other
  •   N/A
  •   N/A
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Primary Outcome

Evaluation of potential biological biomarkers and their correlation with the clinical outcome of radiotherapy

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Secondary Outcome

Identification of biomarkers for a prospective study

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Countries of Recruitment

  •   Germany
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Locations of Recruitment

  • [---]*
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Recruitment

  •   Actual
  •   2014/01/01
  •   600
  •   Multicenter trial
  •   National
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Inclusion Criteria

  •   Both, male and female
  •   no minimum age
  •   no maximum age
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Additional Inclusion Criteria

complete records and samples from patients from the participating centers DKTK

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Exclusion Criteria

no complete records and samples

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Addresses

  • start of 1:1-Block address primary-sponsor
    • Klinik für Strahlenheilkunde
    • Ms.  Prof. Dr. med.  A.  Grosu 
    • Robert-Koch-STr. 3
    • 79106  Freiburg
    • Germany
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    • Klinik f. Strahlenheilkunde
    • Mr.  Prof. Dr. med.  Michael  Henke 
    • Robert-Koch-Str. 3
    • 79106  Freiburg
    • Germany
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  • start of 1:1-Block address public-contact
    • Klinik f. Strahlenheilkunde
    • Mr.  Prof. Dr. med.  Michael  Henke 
    • Robert-Koch-Str. 3
    • 79106  Freiburg
    • Germany
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Sources of Monetary or Material Support

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    • Klinik für Strahlenheilkunde
    • Ms.  Prof. Dr. med.  A.  Grosu 
    • Robert-Koch-STr. 3
    • 79106  Freiburg
    • Germany
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Status

  •   Recruiting complete, follow-up complete
  •   2014/12/17
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Trial Publications, Results and other Documents

  • [---]*
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* This entry means the parameter is not applicable or has not been set.