Trial document



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  DRKS00005277

Trial Description

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Title

Mediators of post-infarct inflammation

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Trial Acronym

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URL of the Trial

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Brief Summary in Lay Language

The aim of this study is to assess different parameters that lead to inflammation after myocardial infarction. Controls with coronary artery disease and no infarction will be used as controls.

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Brief Summary in Scientific Language

Patients after myocardial infarction often suffer from systemic inflammation. In this study blood parameters that lead to systemic inflammation in patients after acute myocardial infarction will be investigated. Results of this study will help to better understand post-infarct inflammation and will persumably allow to improve treatment after myocardial infarction.

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Do you plan to share individual participant data with other researchers?

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Description IPD sharing plan:

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Organizational Data

  •   DRKS00005277
  •   2014/02/14
  •   [---]*
  •   yes
  •   Approved
  •   361/13, Ethik-Kommission der Albert-Ludwigs-Universität Freiburg
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Secondary IDs

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Health Condition or Problem studied

  •   I21 -  Acute myocardial infarction
  •   I25.9 -  Chronic ischaemic heart disease, unspecified
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Interventions/Observational Groups

  •   Inflammatory parameters of serum / plasma will be analyzed in infarct patients.
  •   Inflammatory serum / plasma parameters of patients with coronary artery disease without any signs for myocardial infarction will be assessed.
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Characteristics

  •   Non-interventional
  •   Other
  •   Non-randomized controlled trial
  •   Open (masking not used)
  •   [---]*
  •   Other
  •   Basic research/physiological study
  •   Parallel
  •   N/A
  •   N/A
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Primary Outcome

Differences in inflammatory parameters leading to increased c reactive protein (CRP) in infarct patients.

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Secondary Outcome

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Countries of Recruitment

  •   Germany
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Locations of Recruitment

  • Medical Center 
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Recruitment

  •   Planned
  •   2014/02/15
  •   200
  •   Monocenter trial
  •   National
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Inclusion Criteria

  •   Both, male and female
  •   18   Years
  •   99   Years
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Additional Inclusion Criteria

acute myocardial infarction, stabile coronary artery disease, written informed consent, age >18 years.

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Exclusion Criteria

(hemato-) oncologic diseases, Hb < 9g/dl, age < 18years, no written informed consent.

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Addresses

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    • UHZ Freiburg - Bad KrozingenKardiologie & Angiologie I
    • Mr.  Prof. Dr. med.  Christoph  Bode 
    • Hugstetterstr. 55
    • 79106  Freiburg
    • Germany
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    • Universitätsherzzentrum Freiburg - Bad KrozingenKardiologie & Angiologie I
    • Mr.  Dr.  Philipp  Diehl 
    • Hugstetterstr.55
    • 79106  Freiburg
    • Germany
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    • Universitätsherzzentrum Freiburg - Bad KrozingenKardiologie & Angiologie I
    • Mr.  Dr.  Philipp  Diehl 
    • Hugstetterstr.55
    • 79106  Freiburg
    • Germany
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Sources of Monetary or Material Support

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    • UHZ Freiburg - Bad KrozingenKardiologie & Angiologie I
    • Mr.  Prof. Dr. med.  Christoph  Bode 
    • Hugstetterstr. 55
    • 79106  Freiburg
    • Germany
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Status

  •   Recruiting ongoing
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Trial Publications, Results and other Documents

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* This entry means the parameter is not applicable or has not been set.